Aiming at the problem that Chan-Vese model of face contour extraction has a large amount of calculation and slow segmentation, an parallel algorithm was proposed based on Graphic Processing Unit (GPU) and multi-core CPU with Open Computing Language (OpenCL) parallel programming model. Firstly, by reconstructing the computing architecture, the algorithm could eliminate data dependence of the model; secondly, using OpenCL to parallel and optimize the algorithm. The result shows that, compared with the single-thread method, the proposed algorithm gets a higher average acceleration ratios under NVIDIA GTX660 and AMD FX-8530.